In vitro replication of varicella - zoster virus in 2 human retinal pigment epithelial cells 3 4
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چکیده
35 36 Here we describe for the first time the productive in vitro infection of human retinal pigment 37 epithelial cells by varicella-zoster virus (VZV) resulting in a typical cytopathic effect (CPE) 38 that is characterized by enlarged cells with increased granularity. Depending on CPE 39 dissemination high titres of up to 1.6 x 10 plaque forming units per millilitre of cell-free and 40 cryostable VZV can be recovered. 41
منابع مشابه
In vitro replication of varicella-zoster virus in human retinal pigment epithelial cells.
Here we describe for the first time the productive in vitro infection of human retinal pigment epithelial cells by varicella-zoster virus (VZV), resulting in a typical cytopathic effect (CPE) that is characterized by enlarged cells with increased granularity. Depending on the CPE dissemination, high titers of up to 1.6 x 10(6) PFU of cell-free and cryostable VZV/ml can be recovered.
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